Impaired Spatial Learning is Associated with Disrupted Integrity of the White Matter in Akt3 Knockout Mice
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چکیده
منابع مشابه
Cardiorespiratory fitness is associated with white matter integrity in aging
OBJECTIVE Aging is associated with reduced neural integrity, yet there are remarkable individual differences in brain health among older adults (OA). One factor that may attenuate age-related neural decline is cardiorespiratory fitness (CRF). The primary aim of this study was to link CRF to neural white matter microstructure using diffusion tensor imaging in OA. METHODS Young adults (YA; n = ...
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OBJECTIVE This study investigated white matter integrity in patients with amnestic mild cognitive impairment by diffusion tensor imaging. METHODS A total of 83 patients with amnestic mild cognitive impairment and 85 elderly healthy controls underwent neuropsychological testing and a diffusion tensor imaging scan. Whole-brain white matter data were parcellated into 50 regions based on the anat...
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Diffusion tensor imaging studies in schizophrenia have demonstrated lower diffusion anisotropy within white matter that provides information about brain white matter integrity. We have examined whether white matter is abnormal in first-episode schizophrenia by using diffusion tensor imaging. Twenty-one schizophrenic patients and healthy controls underwent diffusion tensor imaging scans that ana...
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Di¡usion tensor imaging studies in schizophrenia have demonstratedlowerdi¡usion anisotropy withinwhitematter thatprovides information about brain white matter integrity.We have examined whether whitematter is abnormal in ¢rst-episode schizophrenia by using di¡usion tensor imaging. Twenty-one schizophrenic patients and healthy controls underwent di¡usion tensor imaging scans that analyzed by usi...
متن کاملAerobic fitness is associated with gray matter volume and white matter integrity in multiple sclerosis.
Alterations in gray and white matter have been well documented in individuals with multiple sclerosis. Severity and extent of such brain tissue damage have been associated with cognitive impairment, disease duration and neurological disability, making quantitative indices of tissue damage important markers of disease progression. In this study, we investigated the association between cardioresp...
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ژورنال
عنوان ژورنال: CNS Neuroscience & Therapeutics
سال: 2016
ISSN: 1755-5930
DOI: 10.1111/cns.12647